Aportes navales al inicio de la investigación en medicina tropical en el siglo XIX / Naval contributions at the beginning of the tropical medicine research in the 19th century

Resumen En la segunda mitad del siglo XIX, el inicio de la investigación en medicina tropical se vio favorecido con aportes de empresas navieras, como la Compañía Holandesa de las Indias Orientales, siendo quizás el más importante su gestión apoyando la creación en China del Servicio Marítimo Imperial de Aduanas (1854-1950), impuesto al débil gobierno chino por los cónsules de Inglaterra, Francia y EEUU, para establecer tasas regulares en todos sus puertos, que pronto amplió sus funciones a la información de mareas, tifones y clima, terminando por crear en 1863 un Servicio Médico para detectar epidemias y establecer cuarentenas. Este Servicio Médico editó una revista, Medical Reports, en la cual publicaron distinguidos investigadores, como Patrick Manson, Padre de la Medicina Tropical. Comentamos algunos informes aparecidos en ella, para conocer su real importancia en el desarrollo de la medicina tropical.

Abstract In the second half of the 19th century, the beginning of the research on tropical medicine was favored with contributions from shipping companies, like Dutch East India Company, being perhaps the most important of these its collaboration in the creation of the China Imperial Maritime Customs Service (1854-1950), imposed by consuls from England, France and USA, on the weak Chinese government in order to establish regular taxes in all its ports, soon expanding its functions with reports on tides, typhoons and weather, ending up creating a medical service in 1863 to detect epidemics and establish quarantines. This medical service published a Journal, the Imperial Maritime Customs Medical Reports, where they wrote distinguished investigators, such as Patrick Manson, Father of Tropical Medicine. We comment in some reports of this journal, to get an idea about its real importance in the development of tropical medicine.

Women made visible: a different perspective on the history of the Institute of Tropical Medicine in Portugal, 1943-1966 / Mulheres visíveis: uma perspectiva diferente na história do Instituto de Medicina Tropical em Portugal, 1943-1966

Abstract This work focuses on the scientific research conducted by women at Portugal's Institute of Tropical Medicine between 1943 and 1966. The Institute's scientific journal documents the participation of women in tropical medicine during this period. Their publications addressed a variety of subjects and resulted from research carried out in the metropolis as well as Portugal's overseas colonies. Most of the articles written by these women were are co-authored by their male colleagues, reflecting the incorporation of female researchers into scientific networks already established by men. This work in progress provides a starting point to lend visibility to a group of scientific actors who are practically absent from the historiography of tropical medicine.

Resumo O foco deste trabalho é a pesquisa científica realizada por mulheres no Instituto de Medicina Tropical, em Portugal, entre 1943 e 1966. O periódico científico do Instituto documenta a participação das mulheres na medicina tropical nesse período. Suas publicações abordavam uma diversidade de temas e resultaram de pesquisas realizadas na metrópole, bem como nas colônias ultramarinas de Portugal. A maioria dos artigos escritos por mulheres contava com a coautoria de seus colegas homens, refletindo a incorporação de pesquisadoras às redes científicas já estabelecidas por homens. Este trabalho em andamento representa um ponto de partida para dar visibilidade a um grupo de atores científicos que está praticamente ausente da historiografia da medicina tropical.

History of the E.I. Martsinovsky Institute of Medical Parasitology and Tropical Medicine: research on malaria and leishmaniasis / História do Instituto E.I. Martsinovsky de Parasitologia Médica e Medicina Tropical: pesquisa sobre malária e leishmaniose

Abstract This review presents the 100-year history of the Martsinovsky Institute of Medical Parasitology and Tropical Medicine in Moscow, Russia, starting with its foundation and early activities, and also describes the impact of its leading scientists, some of whom became internationally known. The institute headed a network of nine tropical institutes in the various Soviet republics from the 1920s to 1990. The extensive body of literature on the history and research accomplishments of this institute has mainly been published in Russian; our goal here is to introduce these achievements and this expertise to the international scientific and medical community, focusing on malaria and leishmaniasis and the development of measures to control and monitor these diseases in the USSR.

Resumo O artigo analisa a história centenária do Instituto Martsinovsky de Parasitologia Médica e Medicina Tropical em Moscou, Rússia, desde sua fundação e primeiras atividades, e descreve a influência de seus principais cientistas, alguns dos quais viriam a conquistar renome internacional. O instituto liderou uma rede de nove institutos tropicais em diversas repúblicas soviéticas entre as décadas de 1920 e 1990. A vasta literatura sobre o trabalho de história e pesquisa desse instituto foi publicada sobretudo em russo; nosso objetivo aqui é apresentar esse trabalho e conhecimento à comunidade médica e científica internacional, concentrando-se na malária e na leishmaniose e no avanço de medidas de controle e monitoramento dessas doenças na URSS.

"Hipnóticos" na metrópole: africanos no Hospital Colonial de Lisboa nas primeiras décadas do século XX / "Hypnotics" in the metropolis: Africans in the Colonial Hospital of Lisbon during the early twentieth century

Resumo No início do século XX, alguns médicos portugueses foram à África estudar a chamada doença do sono. Entre eles estava Ayres Kopke, membro da primeira missão médica à África Ocidental Portuguesa. De regresso a Lisboa, o professor da Escola de Medicina Tropical continuou suas pesquisas, inclusive por meio da observação de doentes trazidos para a metrópole. Desde 1903, as repartições de saúde nas colônias estavam incumbidas de enviar doentes com determinadas patologias exóticas para o Hospital Colonial de Lisboa. Com base em documentos desse hospital, incluindo fotografias dos doentes, então chamados de hipnóticos, o artigo aborda a importância das experiências com humanos na metrópole para o avanço da medicina tropical durante o colonialismo.

Abstract At the start of the twentieth century, some Portuguese physicians traveled to Africa to study sleeping sickness (African trypanosomiasis). One was Ayres Kopke, a member of the first medical mission to Portuguese West Africa and professor at the School of Tropical Medicine. After returning to Lisbon, Kopke continued his research, which included observation of patients brought to the metropolis. Starting in 1903, health departments in the colonies were responsible for sending patients with certain exotic diseases to the Colonial Hospital of Lisbon. Based on documents from this hospital including photographs of patients (who at that time were called "hypnotics"), this article discusses the importance of human experiments in Lisbon for advances in tropical medicine during the colonial period.

Leishmaniases of the New World from a historical and global perspective, from the 1930s to the 1960s / Leishmanioses do Novo Mundo numa perspectiva histórica e global, dos anos 1930 aos 1960

Abstract The first autochthonous cases of cutaneous and mucocutaneous leishmaniasis in the Americas were described in 1909, but visceral leishmaniasis only erupted as a public health problem in the region in 1934. Today Brazil is the country with the most cases of American tegumentary leishmaniasis, and alongside India has the highest incidence of visceral leishmaniasis. Knowledge production and efforts to control these diseases have mobilized health professionals, government agencies and institutions, international agencies, and rural and urban populations. My research addresses the exchange and cooperation networks they established, and uncertainties and controversial aspects when notable changes were made in the approach to the New World leishmaniases.

Resumo Os primeiros casos de leishmaniose cutânea e mucocutânea autóctones das Américas foram descritos em 1909, e em 1934 a leishmaniose visceral irrompeu como problema de saúde pública na região. O Brasil tem hoje o maior número de casos da leishmaniose tegumentar americana e, junto com a Índia, a mais elevada incidência de leishmaniose visceral. A produção de conhecimentos e os esforços para controlar essas doenças mobilizaram, em nível global, profissionais de saúde, populações urbanas e rurais, instituições governamentais e agências internacionais. Recuperam-se aqui alguns desses agrupamentos, redes de troca e cooperação, incertezas e polêmicas, identificando-se mudanças na abordagem das leishmanioses do Novo Mundo.

Oswaldo Gonçalves Cruz: the character, the scientist, the academician

Abstract The present work analyses some particular aspects of Oswaldo Cruz's unique biography, valuing his work, which was built along a successful physician and scientist professional trajectory and also as a courageous and fortunate formulator of public health policies and of fight strategies against the epidemics that seasonally affected the city of Rio de Janeiro at the beginning of the 20th century. The authors also dwell on his legacy as Head scientist and manager of the Institute that bears his name and became the template for experimental research and medicine in Brazil and the bedrock of the Fundação Oswaldo Cruz, one of the most important Brazilian Institutions devoted to teaching, research, development and production in health. This heritage made possible to overcome the existing dissensions between doctors and scientists to build a sanitary movement committed to the major health problems in Brazil. Finally, the paper explores some features of the character and reports some of his moments during his passage, as a Full Academician, at the Brazilian Academia Nacional de Medicina.

La historiografía de la fiebre amarilla en América Latina desde 1980: los límites del presentismo / The historiography of yellow fever in Latin America since 1980: the limits of presentism

Resumen Este artículo presenta un análisis historiográfico sobre la fiebre amarilla en América Latina. Se muestra que las narrativas dominantes abordan la fiebre a partir de la dicotomía naturaleza-cultura, ya sea que la fiebre sea considerada como un actor histórico o que su historia aparezca vinculada a relaciones de poder. Se exploran algunas historias que asocian la enfermedad con la racialización del discurso de salud pública, la relación entre centros y periferias en la producción de ciencia y la salud pública norteamericana. Se argumenta que esta historiografía fija la naturaleza de la fiebre según el conocimiento médico contemporáneo (presentismo) y se sugiere que nuevos temas y perspectivas podrían emerger de un diálogo con la historia y la sociología de la ciencia.

Abstract This article provides a historiographical analysis of yellow fever in Latin America. It shows that the dominant narratives approach the fever using the nature-culture dichotomy, either treating the fever as an historical actor or linking its history to power relations. This study explores some histories that associate the disease with the racialization of public health discourse, the relationship between centers and peripheries in the production of science, and US public health. It argues that this historiography fixes the nature of the fever according to contemporary medical knowledge (presentism), and suggests that new themes and perspectives might emerge from a dialogue with the history and sociology of science.

The remarkable pioneering contribution of Gaspar Vianna to the study of the neuropathology of Chagas disease / A notável contribuição pioneira de Gaspar Vianna para o estudo da neuropatologia da doença de Chagas

ABSTRACT Gaspar Vianna is considered one of the great names in Medicine and Science in Brazil. Yet, little prominence has been given to his studies in Neuropathology. He was the first to describe, in 1911, the histopathology and pathogenesis of chagasic encephalitis in the acute phase of Chagas disease, as well as the intracellular life cycle of Trypanosoma cruzi. Over 100 years have elapsed and Gaspar Vianna's pioneering study remains an example of a meticulous and still up-to-date description of central nervous system involvement in the acute phase of Chagas disease.

RESUMO Gaspar Vianna é considerado um dos grandes nomes da Medicina e da Ciência no Brasil. Contudo, pouco destaque tem sido dado aos seus estudos em Neuropatologia. Ele foi o primeiro a descrever a histopatologia e a patogênese da encefalite chagásica na fase aguda da doença de Chagas, bem como o ciclo evolutivo intracelular do Trypanosoma cruzi, em 1911. Passados mais de 100 anos, o estudo pioneiro de Gaspar Vianna permanece como exemplo de descrição minuciosa e ainda atual do envolvimento do sistema nervoso central na fase aguda da doença de Chagas.

Aportes del Laboratorio de Micología del Instituto de Medicina Tropical Pedro Kourí al desarrollo de la especialidad en Cuba / Contributions of the Mycology Laboratory at Pedro Kouri Tropical Medicine Institute to the development of the specialty in Cuba

En el marco del 80 aniversario del Instituto de Medicina Tropical Pedro Kourí, se exponen en apretada síntesis, las actividades más relevantes en el campo del diagnóstico, la investigación y la docencia desarrolladas hasta el momento por el Laboratorio de Micología de la referida institución. A 38 años de su creación, este sigue siendo uno de los pocos lugares en Cuba que se desempeña en este campo y que se reconoce por los logros científico-técnicos alcanzados. Sin lugar a duda, estos responden básicamente al cuadro de salud nacional, sin descuidar el entorno regional y mundial. Todos los resultados que se exponen, se encuentran sustentados por más de 100 publicaciones y otras obras científicas, lo que avala la calidad y rigor del trabajo desplegado. Sirva este artículo para homenajear al fundador del Instituto de Medicina Tropical Pedro Kourí y a todos los científicos que en el transcurso de estos años contribuyeron a engrandecer su nombre(AU)

In the framework of the 80th anniversary of Pedro Kouri Tropical Medicine Institute, a succinct presentation is provided of the most relevant activities in the fields of diagnosis, research and teaching so far performed by the Mycology Laboratory at the Institute. Thirty-eight years after its founding, the Laboratory continues to be one of the few places in Cuba devoted to this field and recognized for its scientific and technical achievements, which no doubt essentially respond to the national health status, without neglecting the regional and global environment. All the results presented are endorsed by over 100 publications and scientific works, which is evidence of the quality and rigor of the work done. May this paper be a tribute to the founder of Pedro Kouri Tropical Medicine Institute and all the scientists who have brought prestige to its name throughout these years(AU)

Trópicos, ciência e leishmanioses: uma análise sobre circulação de saberes e assimetrias / The tropics, science, and leishmaniasis: an analysis of the circulation of knowledge and asymmetries

Resumo: O artigo investiga o processo de circulação de saberes ocorrido, nas primeiras décadas do século XX, entre os pesquisadores sul-americanos Edmundo Escomel (Peru) e Alfredo Da Matta (Brasil) e os europeus Alphonse Laveran (França) e Patrick Manson (Inglaterra) no que diz respeito à definição e validação da espundia como uma enfermidade particularizada da América do Sul, ao mesmo tempo que se postulava a necessidade do seu enquadramento no recém-criado grupo de moléstias denominado "leishmanioses". Compartilhando a recente preocupação em pensar a pesquisa histórica para além dos limites impostos pelo Estado nacional como categoria organizadora da narrativa, dialoga com alguns apologistas da história global/transnacional situando o caso específico nessa perspectiva analítica.

Abstract: The article investigates the process of circulation of knowledge which occurred during the first decades of the twentieth century between the South American researchers Edmundo Escomel (Peru) and Alfredo Da Matta (Brazil) and the Europeans Alphonse Laveran (France) and Patrick Manson (England) with regard to the definition and validation of espundia as a disease specific to South America, while simultaneously the need to insert this illness into the newly created group of diseases called the "leishmaniasis" was proposed. Sharing recent concerns in considering historical research beyond the limits imposed by the Nation-state as a category that organizes narratives, it dialogs with some apologists of global and transnational history, situating this specific case within this analytical perspective.

O lugar da medicina tropical nas dissertações da escola médica portuense, 1875-1923 / The role of tropical medicine in the dissertations of the Porto school of medicine, 1875-1923

Desde 1827 a Escola Médico-Cirúrgica do Porto publicou centenas de teses inaugurais dedicadas a uma grande variedade de temas de natureza médica. Tendo em atenção a predominância da escola de Lisboa na elaboração de um conhecimento científico próprio na área da medicina tropical, o contributo do estabelecimento portuense pode ser considerado residual em termos comparativos. No entanto, entre 1875 e 1923, existem fontes documentais que versam a temática das doenças tropicais, em particular do paludismo/sezonismo. Com este trabalho, pretende-se mostrar os contributos aportados pela Escola Médico-Cirúrgica do Porto a um tema que à partida não despertou um particular interesse dos médicos nortenhos, analisando e enquadrando a produção científica em redor da medicina tropical.

Since 1827 the Escola Médico-Cirúrgica of Porto published hundreds of inaugural dissertations dedicated to a broad range of subjects of medical nature. Bearing in mind the prevalence of the Lisbon school in the elaboration of its own scientific knowledge in the field of tropical medicine, the contribution of the Porto establishment may well be considered residual in comparative terms. However, between 1875 and 1923, there are documentary sources that address tropical diseases, particularly malaria. This work purports to show the contributions made by the Escola Médico-Cirúrgica of Porto to a theme which initially did not arouse specific interest of northern Portuguese physicians, duly analyzing and defining the scientific output in the field of tropical medicine.

Public health and tropical modernity: the combat against sleeping sickness in Portuguese Guinea, 1945-1974 / Saúde pública e modernidade tropical: o combate à doença do sono na Guiné Portuguesa, 1945-1974

Until the establishment of the “Commission for the study of and combat against sleeping sickness” (Missão de estudo e combate à doença do sono) in 1945, underfunded and understaffed health services had not been a priority for the colonial administration in Portuguese Guinea. The Commission not only implemented endemic disease control in the territory under the auspices of metropolitan institutions, but also provided preventive public healthcare to the local population. Its relative success in reducing the negative impact of Human African Trypanosomiasis turned the colony into an apparent model of tropical modernity. In the process, the local evolution of the disease was marginalized, despite the tacit but contested recognition by some health professionals of the role of popular healthcare.

Os serviços de saúde que sofreram de uma crónica falta de recursos humanos e materiais nunca foram uma prioridade para a administração colonial na Guiné Portuguesa até a criação da Missão de Estudo e Combate à Doença do Sono em 1945. Além de introduzir o controlo de doenças endémicas sob a tutela de instituições metropolitanas, a Missão também providenciou cuidados preventivos de saúde pública para as populações locais. O sucesso relativo da redução do impacto nocivo da tripanossomíase africana parece ter transformado a colónia num modelo de modernidade tropical. Porém, as trajetórias locais da doença foram marginalizadas, apesar do reconhecimento tácito mas contestado por profissionais de saúde do papel de cuidados populares de saúde.